ISSN (Print):
1570-1808
ISSN (Online):
1875-628X
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Letters in Drug Design & Discovery

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Volume 21 , Issues 16, 2024

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Volume 17, Issue 7, 2020


Biography

Meet Our Editorial Board Member

Pp: 827-827
Author(s): Lídia Moreira Lima
DOI: 10.2174/157018081707200620124206

Research Article

Synthesis of Indolyl Pyrazole Scaffolds as Potential Anti-cancer Agents and their Molecular Modelling Studies

Pp: 828-839
Author(s): Ganga Reddy Gaddam, Pramod Kumar Dubey and Venkata Ramana Reddy Chittireddy*
DOI: 10.2174/1570180816666191024103534

Research Article

Development of Novel Glitazones as Antidiabetic Agents: Molecular Design, Synthesis, Evaluation of Glucose Uptake Activity and SAR Studies

Pp: 840-849
Author(s): Mahendra Gowdru Srinivas, Prabitha Prabhakaran, Subhankar Probhat Mandal, Yuvaraj Sivamani, Pranesh Guddur and Bommenahally Ravanappa Prashantha Kumar*
DOI: 10.2174/1570180816666191105124535

Research Article

Understanding the Binding Mechanism of Antagonist (AZD3293) Against BACE-1: Molecular Insights into Alzheimer’s Drug Discovery

Pp: 850-857
Author(s): Sphelele Sosibo*, Daniel Gyamfi Amoako, Anou Moise Somboro, Darren Delai Sun, Jane Catherine Ngila and Hezekiel Kumalo*
DOI: 10.2174/1570180816666191029142640

Research Article

Enhancement Effect of Zn-Arsenazo III Complex for G-quadruplex DNA Stability of Proto-oncogene Promoter Telomeres

Pp: 858-866
Author(s): Liyuan Zou, Hongbo Li*, Mingbin Liu, Weihua Zhao and Suqin Wang*
DOI: 10.2174/1570180816666191112154141

Research Article

Discovery of 2-aminopyridine Derivatives with Antichagasic and Antileishmanial Activity Using Phenotypic Assays

Pp: 867-872
Author(s): Daiane Yukie Tezuka, Sergio de Albuquerque, Carlos Alberto Montanari and Andrei Leitão*
DOI: 10.2174/1570180816666191204105232

Research Article

Synthesis, Biological Evaluation and Molecular Modeling Studies of Novel C (7) Modified Analogues of Chrysin

Pp: 873-883
Author(s): Pulabala Ramesh, Vankadari Srinivasa Rao, Puchakayala Muralidhar Reddy*, Katragadda Suresh Babu and Mutheneni Srinivasa Rao
DOI: 10.2174/1570180816666190913183623

Research Article

Design and Synthesis of 4(1H)-quinolone Derivatives as Autophagy Inducing Agents by Targeting ATG5 Protein

Pp: 884-890
Author(s): Yifan Jia, Difei Yu, Qiuhua Huang, Xiaodong Zhang, Liqin Qiu, Rihui Cao*, Runlei Du* and Wenbin Liu*
DOI: 10.2174/1570180816666191122113045

Research Article

Synthesis and Evaluation of α-Asaronol Esters with LDH and GABAA Receptor Modulation as Anticonvulsant Agents

Pp: 891-904
Author(s): Yajun Bai, Bin Li, Jing Xie, Xufei Chen, Shu Cheng, Yujun Bai, Ying Sun, Fanggang Qin, Jing Liang, Yanrui Ding* and Xiaohui Zheng*
DOI: 10.2174/1570180816666191204104127

Research Article

Searching for Potential HDAC2 Inhibitors: Structure-activity Relationship Studies on Indole-based Hydroxamic Acids as an Anticancer Agent

Pp: 905-917
Author(s): Ekta Shirbhate, Divya, Preeti Patel, Vijay K. Patel, Ravichandran Veerasamy, Prabodh C. Sharma and Harish Rajak*
DOI: 10.2174/1570180817666200103125701

Letter Article

Facile Synthesis of 6-Phenyl-6h-chromeno [4, 3-b] Quinoline Derivatives using NaHSO4@SiO2 Re-usable Catalyst and Their Antibacterial Activity Study Correlated by Molecular Docking Studies

Pp: 929-938
Author(s): Kancharla Suman, Jyothi Prashanth , Koya Prabhakara Rao*, Madala Subramanyam, Vejendla Anuradha and Mandava Venkata Basaveswara Rao
DOI: 10.2174/1570180816666190731115809

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