Abstract
Background: Segmental medial arteriolysis (SAM) is a unique arteriopathy highlighted by significant lytic changes in the medial wall of the blood vessels and can present from vague gastrointestinal discomfort to catastrophic abdominal bleeding and shock. We hereby present a concise review of this rare phenomenon with historic perspectives, epidemiology, and current concepts of etiology, pathogenesis, relevant clinical associations, treatment modalities, prognosis and future directions in SAM.
Conclusion: In addition, we present an interesting occurrence of this intriguing phenomenon in a forty-eight year old lady at our institution who presented with vague symptomatology and was an extremely challenging diagnosis. This highlights the importance of timely detection and institution of therapeutic or preventive strategies to minimize future catastrophic events.
Keywords: Intriguing, mediolysis, segmental arterial, arteriopathy, stenoses, hyperlipidemia.
Cardiovascular & Hematological Disorders-Drug Targets
Title:The Intriguing Occurrence of Segmental Arterial Mediolysis: Case Report and Concise Literature Review
Volume: 17 Issue: 2
Author(s): Muhammad Ali Chaudhry *
Affiliation:
- Aultman Hospital, Canton, OH-44710,United States
Keywords: Intriguing, mediolysis, segmental arterial, arteriopathy, stenoses, hyperlipidemia.
Abstract: Background: Segmental medial arteriolysis (SAM) is a unique arteriopathy highlighted by significant lytic changes in the medial wall of the blood vessels and can present from vague gastrointestinal discomfort to catastrophic abdominal bleeding and shock. We hereby present a concise review of this rare phenomenon with historic perspectives, epidemiology, and current concepts of etiology, pathogenesis, relevant clinical associations, treatment modalities, prognosis and future directions in SAM.
Conclusion: In addition, we present an interesting occurrence of this intriguing phenomenon in a forty-eight year old lady at our institution who presented with vague symptomatology and was an extremely challenging diagnosis. This highlights the importance of timely detection and institution of therapeutic or preventive strategies to minimize future catastrophic events.
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Cite this article as:
Chaudhry Ali Muhammad *, The Intriguing Occurrence of Segmental Arterial Mediolysis: Case Report and Concise Literature Review, Cardiovascular & Hematological Disorders-Drug Targets 2017; 17 (2) . https://dx.doi.org/10.2174/1871529X17666170703115833
DOI https://dx.doi.org/10.2174/1871529X17666170703115833 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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