Abstract
Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.Keywords: Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.
Infectious Disorders - Drug Targets
Title:A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy
Volume: 17 Issue: 3
Author(s): Márcia M. R. Teixeira, Claudia B. Assunção, Sandra Lyon, Renata R. Gomes, Hyllo B.M. Junior, Fabiana Rocha-Silva, Sônia M. de Figueiredo, Amanda Sanchez Machado, Elen R.R. Teixeira, Adriana S. Carneiro, Rogério J.M.B. Júnior, Vânia A. Vicente and Rachel B. Caligiorne*
Affiliation:
- Núcleo de Pós- Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG,Brazil
Keywords: Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.
Abstract: Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.Export Options
About this article
Cite this article as:
Teixeira M. R. Márcia , Assunção B. Claudia, Lyon Sandra , Gomes R. Renata , Junior B.M. Hyllo , Rocha-Silva Fabiana, de Figueiredo M. Sônia, Machado Sanchez Amanda , Teixeira R.R. Elen , Carneiro S. Adriana, Júnior J.M.B. Rogério, Vicente A. Vânia and Caligiorne B. Rachel *, A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy, Infectious Disorders - Drug Targets 2017; 17 (3) . https://dx.doi.org/10.2174/1871526517666170530124905
DOI https://dx.doi.org/10.2174/1871526517666170530124905 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Anti-Inflammatory Iridoids of Botanical Origin
Current Medicinal Chemistry Application of NMR Spectroscopy in Medicinal Chemistry and Drug Discovery
Current Topics in Medicinal Chemistry Regulation of Protective and Pathogenic Th17 Responses
Current Immunology Reviews (Discontinued) Acanthamoeba-Bacteria: A Model to Study Host Interaction with Human Pathogens
Current Drug Targets Drainage of Cerebral Abscesses Prior to Valve Replacement in Stable Patients with Acute Left-Sided Infective Endocarditis
CNS & Neurological Disorders - Drug Targets A New Strategy to Destroy Antibiotic Resistant Microorganisms: Antimicrobial Photodynamic Treatment
Mini-Reviews in Medicinal Chemistry Processed Foods, Dysbiosis, Systemic Inflammation, and Poor Health
Current Nutrition & Food Science Adverse Events of Proton Pump Inhibitors: Potential Mechanisms
Current Drug Metabolism Longitudinal Molecular Imaging of Burn Wound Healing: Effect of Staphylococcus aureus, or Lack of Tumor Necrosis Factor (TNF) or Interleukin-6 (Il-6)
Current Molecular Imaging (Discontinued) Radix Astragali (Astragalus): Latest Advancements and Trends in Chemistry, Analysis, Pharmacology and Pharmacokinetics
Current Organic Chemistry Immunomodulatory Effects of <i>Allium sativum</i> L. and its Constituents against Viral Infections and Metabolic Diseases
Current Topics in Medicinal Chemistry Anesthesia Issues in Central Nervous System Disorders
Current Aging Science A Pharmacological Review of Five Widely Used Traditional Medicinal Plants for Sedative-Hypnotic Effects in Bangladesh
Current Traditional Medicine Infection and Malignancy Risk in Patients Treated with TNF Inhibitors for Immune-Mediated Inflammatory Diseases
Current Drug Safety Role of ABC Transporters in Veterinary Medicine: Pharmaco- Toxicological Implications
Current Medicinal Chemistry Biological and Pharmacological Activities of Iridoids: Recent Developments
Mini-Reviews in Medicinal Chemistry An Overview of Bioactive Peptides for in vivo Imaging and Therapy in Human Diseases
Mini-Reviews in Medicinal Chemistry Therapeutic Indications and Action Mechanisms of Bilirubin: Suggestions from Natural Calculus Bovis
Current Signal Transduction Therapy Case Series and Mini-Review on Elizabethkingia meningoseptica, A high Alert Organism Causing Meningitis in Premature Neonates from A Tertiary Care Hospital of Western Rajasthan
Infectious Disorders - Drug Targets Percutaneous Treatment of Hydatid Liver Cysts: An Update
Recent Patents on Anti-Infective Drug Discovery