Review Article

Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition

Author(s): Pei-Yu Chen and Michael Simons

Volume 17, Issue 15, 2016

Page: [1707 - 1713] Pages: 7

DOI: 10.2174/1389450117666160502151308

Price: $65

Abstract

Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.

Keywords: Endothelial cell, endothelial to mesenchymal transition, EndMT, TGFβ, FGF.

Graphical Abstract

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy