Abstract
Chronic wounds and ulcers are posing a devastating manifestation on the socioeconomic status across the globe along with the patient compliance. It reinforces a need for the development of successful alternative treatments for the chronic wound care and ulcer management practices. This review explores the progressive developments being made in the fabrication of electrospun nanofibrous scaffolds towards elimination of microbial infection from chronic wounds to accelerate the wound healing process. Functional three dimensional nanofibrous scaffolds produced by electrospinning have great potential in a wide spectrum of biomedical practices, such as tissue engineering, drug/gene delivery and wound dressing. Moreover, this review also highlights the materials and post modification methods, such as the functionaliation of electrospun nanofibrous scaffolds using growth factors, so that such smart and bioactive nanofibrous scaffolds could be made suitable for wound healing applications.
Keywords: Chronic wounds, ulcer management, electrospun, nanofibrous scaffolds, wound healing, electrospinning, wound dressing, growth factors.
Current Pharmaceutical Design
Title:Nanofibre Based Smart Pharmaceutical Scaffolds for Wound Repair and Regenerations
Volume: 22 Issue: 11
Author(s): Charu Dwivedi, Himanshu Pandey, Avinash C. Pandey and Pramod W. Ramteke
Affiliation:
Keywords: Chronic wounds, ulcer management, electrospun, nanofibrous scaffolds, wound healing, electrospinning, wound dressing, growth factors.
Abstract: Chronic wounds and ulcers are posing a devastating manifestation on the socioeconomic status across the globe along with the patient compliance. It reinforces a need for the development of successful alternative treatments for the chronic wound care and ulcer management practices. This review explores the progressive developments being made in the fabrication of electrospun nanofibrous scaffolds towards elimination of microbial infection from chronic wounds to accelerate the wound healing process. Functional three dimensional nanofibrous scaffolds produced by electrospinning have great potential in a wide spectrum of biomedical practices, such as tissue engineering, drug/gene delivery and wound dressing. Moreover, this review also highlights the materials and post modification methods, such as the functionaliation of electrospun nanofibrous scaffolds using growth factors, so that such smart and bioactive nanofibrous scaffolds could be made suitable for wound healing applications.
Export Options
About this article
Cite this article as:
Dwivedi Charu, Pandey Himanshu, Pandey C. Avinash and Ramteke W. Pramod, Nanofibre Based Smart Pharmaceutical Scaffolds for Wound Repair and Regenerations, Current Pharmaceutical Design 2016; 22 (11) . https://dx.doi.org/10.2174/1381612822666151215103553
DOI https://dx.doi.org/10.2174/1381612822666151215103553 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Recommendations for Severe Hypertriglyceridemia Treatment, are there New Strategies?
Current Vascular Pharmacology Immune Function in Pregnant Women with Affective Disorders
Current Psychiatry Reviews Nanoparticles in Biomedicine: New Insights from Plant Viruses
Current Medicinal Chemistry Implications of FLT3 Mutations in the Therapy of Acute Myeloid Leukemia
Reviews on Recent Clinical Trials Fanconi Anemia Proteins, DNA Interstrand Crosslink Repair Pathways, and Cancer Therapy
Current Cancer Drug Targets Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion
Current Drug Targets Clinical Applications of Mesenchymal Stem Cells in the Treatment of Fracture Non-Union and Bone Defects
Current Stem Cell Research & Therapy Mucosal Vaccine Vectors: Replication-Competent Versus Replication-Deficient Poxviruses
Current Pharmaceutical Design Rallying the Troops: Innate Mucosal Responses to Enteric Pathogens
Current Immunology Reviews (Discontinued) Preclinical Analyses of the Therapeutic Potential of Allopregnanolone to Promote Neurogenesis In Vitro and In Vivo in Transgenic Mouse Model of Alzheimers Disease
Current Alzheimer Research HIV Extracellular Tat: Myth or Reality?
Current HIV Research The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide
Recent Patents on Anti-Cancer Drug Discovery Parkinson’s Disease and Alpha-Synucleinopathies: from Arising Pathways to Therapeutic Challenge
Central Nervous System Agents in Medicinal Chemistry B Cell Modulation Strategies in Autoimmunity: The SLE Example
Current Pharmaceutical Design Restoration of the Striatal Dopamine Synthesis for Parkinsons Disease:Viral Vector-Mediated Enzyme Replacement Strategy
Current Gene Therapy Stem Cell Niche in Tissue Homeostasis, Aging and Cancer
Current Medicinal Chemistry Defining a Role for Mucosal Immunity in the Prevention and Pathogenesis of Respiratory Allergic Diseases
Current Immunology Reviews (Discontinued) Melatonin as Antioxidant Under Pathological Processes
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Binding Sites of Amyloid β-Peptide in Cell Plasma Membrane and Implications for Alzheimers Disease
Current Protein & Peptide Science The Regulation of FoxP3-Expressing Regulatory T Cells
Endocrine, Metabolic & Immune Disorders - Drug Targets