Abstract
Nano-sized silver powders coated with sodium oleate (NanoAg@C18) was prepared by a simple wet chemical route and characterized by FT-IR, DTA-TG, TEM, SAED and EDS. The main objective of this research was to successfully employ the NanoAg@C18 for the inhibition of bacterial and fungal biofilms in vitro development on catheter sections with a film-coated surface. The lower value of the relative microbial biomass formed on the surface of the modified prosthetic devices demonstrates the anti-biofilm efficiency of the NanoAg@C18 coating and the potential use of this nanosytem for obtaining improved medical devices.
Keywords: Silver nanoparticle, Antibiofilm, Modified prosthetic devices, Surface modification
Current Organic Chemistry
Title:Prosthetic Devices with Functionalized Anti-biofilm Surface Based NanoAg@C18
Volume: 17 Issue: 2
Author(s): Dan Eduard Mihaiescu, Alexandru Mihai Grumezescu, Ecaterina Andronescu, Georgeta Voicu, Anton Ficai, Otilia Ruxandra Vasile, Coralia Bleotu and Crina Saviuc
Affiliation:
Keywords: Silver nanoparticle, Antibiofilm, Modified prosthetic devices, Surface modification
Abstract: Nano-sized silver powders coated with sodium oleate (NanoAg@C18) was prepared by a simple wet chemical route and characterized by FT-IR, DTA-TG, TEM, SAED and EDS. The main objective of this research was to successfully employ the NanoAg@C18 for the inhibition of bacterial and fungal biofilms in vitro development on catheter sections with a film-coated surface. The lower value of the relative microbial biomass formed on the surface of the modified prosthetic devices demonstrates the anti-biofilm efficiency of the NanoAg@C18 coating and the potential use of this nanosytem for obtaining improved medical devices.
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Eduard Mihaiescu Dan, Mihai Grumezescu Alexandru, Andronescu Ecaterina, Voicu Georgeta, Ficai Anton, Ruxandra Vasile Otilia, Bleotu Coralia and Saviuc Crina, Prosthetic Devices with Functionalized Anti-biofilm Surface Based NanoAg@C18, Current Organic Chemistry 2013; 17 (2) . https://dx.doi.org/10.2174/1385272811317020005
DOI https://dx.doi.org/10.2174/1385272811317020005 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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