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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Prosthetic Devices with Functionalized Anti-biofilm Surface Based NanoAg@C18

Author(s): Dan Eduard Mihaiescu, Alexandru Mihai Grumezescu, Ecaterina Andronescu, Georgeta Voicu, Anton Ficai, Otilia Ruxandra Vasile, Coralia Bleotu and Crina Saviuc

Volume 17, Issue 2, 2013

Page: [105 - 112] Pages: 8

DOI: 10.2174/1385272811317020005

Price: $65

Abstract

Nano-sized silver powders coated with sodium oleate (NanoAg@C18) was prepared by a simple wet chemical route and characterized by FT-IR, DTA-TG, TEM, SAED and EDS. The main objective of this research was to successfully employ the NanoAg@C18 for the inhibition of bacterial and fungal biofilms in vitro development on catheter sections with a film-coated surface. The lower value of the relative microbial biomass formed on the surface of the modified prosthetic devices demonstrates the anti-biofilm efficiency of the NanoAg@C18 coating and the potential use of this nanosytem for obtaining improved medical devices.

Keywords: Silver nanoparticle, Antibiofilm, Modified prosthetic devices, Surface modification

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